The important topic of cybersecurity relative to the fight against corruption in the context of global challenges in the pandemic and post-pandemic world requires further research. The purpose of this article is to identify and analyze current and prospective cybersecurity issues in this context by applying general-scientific and special-legal methods of cognition. Using the dialectical method, theoretical background, and contemporary views on ensuring cybersecurity served to investigate the key current challenges. Formal-legal and comparative methods allowed to recommend measures to enhance cybersecurity in view of the massive digitalization and social transformations. The authors emphasize the need to establish a national cybersecurity policy based on society’s information literacy and culture, combining respect to traditional and historical values with a modern understanding of multicultural communication and well-being.